I can confirm this issue with the following hardware and software configuration:
System Configuration:
Processor: Intel Core i5 CPU M560 @2.67GHz
Installed Memory: 2.00 GB (1.6 usable)
Operating System: Windows 7 Home Premium 64 bit

Apache Open Office:
AOO412m3(Build:9782)  -  Rev. 1709696
2015-10-21 09:53:29 (Mi, 21 Okt 2015)
Language: en_US
Additional Language Packs: None

Tried opening the document both by double clicking on it and using File->Open from the OpenOffice main screen. Both resulted in the immediate display of the recovery screen with no document offered to recover. When allowing the recovery to continue it brings up the Main AOO screen.

(In reply to ferdinando.pucci from comment #0)
> Created attachment 85540 [details]
> file that generates the issue

Note that this document was produced (as an .odt) from Microsoft Office Word.

It will take more analysis to see how AOO is failing with it.

(In reply to orcmid from comment #2)
> (In reply to ferdinando.pucci from comment #0)
> > Created attachment 85540 [details]
> > file that generates the issue
> 
> Note that this document was produced (as an .odt) from Microsoft Office Word.
> 
> It will take more analysis to see how AOO is failing with it.

I confirm that both AOO 4.1.2 and Libre Office 5.0.0 fail to open the document on Windows 10 Pro x64.

The .odt document opens successfully in Microsoft Office Word 2016.  It is presented as a 12 page document that describes a medical research protocol to be conducted with laboratory animals, for submission to an animal-use protocol review committee.

There are some highlighted areas and at least one comment from a reviewer.  It appears that the reviewer created the .odt.

Also, the page footer and perhaps a first-page header carries an image and also the "Page n of 12" likely auto-numbering. 

(The submitter for this issue is identified as one of the principal investigators of the research.)

While identification of the defect and problem this proposes for interoperability using OpenDocument Format (.odt), a short-term workaround is probably best for the users of the document.

ADDITIONAL TEST RESULTS

Using Microsoft Word 2016 to save the document as a .doc and as a .docx appears to succeed although the pagination is not preserved exactly.

The .doc opens successfully in AOO 4.1.2.  I have not examined the details but there are no obvious gross defects.  The .docx opens but is not usable, with serious formatting problems.